The inflammatory action is described as a chain of events that arise in response to noxious stimuli, infection or trauma. Various botanical species and plant parts comprise a diverse array of polyphenolic non-steroidal phytochemicals that are incorporated as floral pigments for the attraction of insects as their pollination. Various autoimmune disorders are defined by distinct inflammation and associated failure of the repair process. Pro-inflammatory molecules like TNF, certain interleukins, prostaglandins and even pathogenic concentration of nitric oxide are instrumental in raising such response. More interestingly, nitric oxide has been shown to have the ability to stimulate COX-2 showing a potential synergism. Bryophyllum pinnatum commonly known in some parts of Africa as “good luck” or “resurrection plant”, often used as an herbal remedy for human disorders, including: hypertension, diabetes mellitus, rheumatism, joint pains, insect bites, arthritis, bruises, wounds, boils, abscesses, headaches, and body pains. The leaves are also used for inguinal lymphadenitis and ear diseases. Rue contains different active compounds, out of them rutin, a flavonoid, is known to have nitric oxide scavenging activity.
Cancer-signalling networks are typically complex which involves gene regulation, signalling, cell metabolism, and the alterations in its dynamics caused by the several different types of mutations leading to malignancy. Computational model of networks make possible to understand the complex behaviour of cancer-signalling network. Correlation between complexity (clustering coefficient) of cancer-signalling network pathway and Cancer Epidemiological data sets (Cancer incidence, Death rate and lifetime risk of cancer) has been validated. Results of study support the initial assumption, that the complexity of network matrices is a direct indicator of cancer threat. Understanding the differential behaviour of regulatory networks during health, disease and in response to drugs play a crucial role to enhance drug development efforts, new target identification, delineation of off-target effects, methods of disease prediction, combinatorial drug regimens and also in development of molecularly targeted personalized treatment.
This paper describes our first undergraduate project experience, final report and findings on the subject matter. Initially according to our project title, we were focused on developing a low cost detector which can detect radiation only. To make one of these kinds of detector doesn’t take much and can be prepared at fairly low cost being very common project in nuclear science arena. The Geiger-Muller tube, or GM tube, is an extremely useful and inexpensive way to detect radiation. While the GM tube can only detect the presence and intensity of radiation, this is often all that is needed.
Pineapple in Côte d’Ivoire is going through problems of various origins. Reviving this state imperatively requires both to clean up the plant material and to select varieties which easily adapt to the current pedoclimatic conditions of growing areas. This work assesses the impact of salinity on regenerated pineapple plants by somatic embryogenesis. The tests were carried out in polyethylene bags filled with sea sand, under semi-controlled conditions. Regenerated pineapple plants were watered with six saline solutions (2, 4, 6, 8, 10 and 14 g/L). Control plants were watered with water. The results revealed that salt stress reduces the studied morphophysiological parameters (number of leaves and roots, length of leaves and roots, chlorophyll a, chlorophyll b and total chlorophyll content, the carotenoids content and the relative water content). Pineapple tolerates low salt levels (2 and 4 g/L). However, important disturbances were observed in the metabolism of stressed plants with high levels of NaCl (6 and 10 g/L). As an adaptation strategy to maintain its metabolism from this stress, pineapple responded by accumulating proline. The highest saline content (14 g/L) was found to be lethal for pineapple plants.